Steroids esterified in position 17 and thioesterified in positio

Details Steroids esterified in position 17 and thioesterified in positio Steroids esterified in position 17 and thioesterified in positio

1982-07-13

1984-01-24

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26039745, A61K 3156, C07J 700

Patent

active

044276710

ABSTRACT:
Compounds of formula: ##STR1## wherein A and B each represent, independently of each other, a straight-chained or branched alkyl group having from 1 to 6 carbon atoms or a phenyl group optionally mono- or polysubstituted by alkyl radicals having from 1 to 6 carbon atoms, alkoxy groups having from 1 to 6 carbon atoms or halogen, T and U, independently of each other, represent hydrogen atoms or together form a double bond, V is a hydrogen atom or a methyl group at the .alpha.-position, W is a hydrogen atom or a halogen atom at the .alpha.-position, X is a hydroxy group at the .beta.-position and Y is a hydrogen atom or X and Y may together represent an oxygen atom, and Z.sub.1 is a hydrogen atom, a methyl group at the .alpha.- or .beta.-position, while Z.sub.2 is a hydrogen atom, or Z.sub.1 and Z.sub.2 together form a methylene group. These compounds have anti-inflammatory activity.

REFERENCES:
patent: 3312591 (1967-04-01), Elks et al.
patent: 4243664 (1981-01-01), Annen et al.
patent: 4269778 (1981-05-01), Torossian et al.
patent: 4343739 (1982-08-01), Villax et al.
patent: 4361558 (1982-11-01), Wieland

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