Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1986-07-21
1988-09-13
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
2603973, C07J 100, A61K 3156
Patent
active
047710438
ABSTRACT:
The invention relates to 6-substituted androsta-1,4-diene-3,17-dione derivatives wherein the 6 substituent is an azido, amino or substituted amino group.
The invention provides also a process for preparing the said compounds and pharmaceutical compositions containing same.
The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone-dependent tumors.
REFERENCES:
patent: 3014932 (1961-12-01), Ringold et al.
patent: 3239510 (1966-03-01), Sasaki
patent: 3320291 (1967-05-01), Andreades et al.
patent: 3781276 (1973-12-01), Shapiro
patent: 4028348 (1977-06-01), Bite et al.
Cancer Research (Suppl.) 42, 3327s-3333s (1982); Covey et al.
J.C.S. Chem. Comm. (1973), pp. 72-73; Herzog et al.
D'Alessio Roberto
Di Salle Enrico
Faustini Franco
Lombardi Paolo
Villa Vittoria
Farmitalia Carlo Erba S.p.A.
Lipovsky Joseph A.
Schenkman Leonard
LandOfFree
Steroidic aromatase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Steroidic aromatase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroidic aromatase inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-807087