Steroidal glycolipids as host resistance stimulators against vir

Details Steroidal glycolipids as host resistance stimulators against vir Steroidal glycolipids as host resistance stimulators against vir

1987-06-18

1990-07-17

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 5, 536 62, 514885, A61K 31705

Patent

active

049421549

ABSTRACT:
Disclosed are steroidal derivatives of glycolipids, in which steroids are bridged, via a medium length hydrocarbon chain, to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses that protect an immunocompromised host, particularly resulting from an AIDS-related virus, against opportunistic infection.

REFERENCES:
patent: 4189471 (1980-02-01), Ponpipom et al.
patent: 4228274 (1980-10-01), Ponpipom et al.
patent: 4229441 (1980-10-01), Bugianesi et al.
patent: 4259324 (1981-03-01), Ponpipom et al.
patent: 4301152 (1981-11-01), Ponpipom
patent: 4652553 (1987-03-01), Hagmann et al.
patent: 4652637 (1987-03-01), Hagmann et al.
Chabala et al; Carbohydrate Research vol. 67:55-63 (1978).
Ponpipom et al; Canadian Journal of Chemistry vol. 58, 214-220 (1980).
Ponpipom et al; Journal of Medicinal Chemistry, vol. 23. No. 11, pp. 1184-1188 (1980).
Dagani; Chemical and Engineering News, Dec. 8, 1986, pp. 7-14.
Chem. Abstracts, vol. 99, 1983, 122792Z, Ponpipom et al.
Chem Abstracts, vol. 90, 1979, 23588v, Chabala et al.
Chem Abstracts, vol. 94, 1981, 180690x, Merck.
Chem Pharm. Bull Jap., vol. 12, pp. 528-532, 1964.
P.N.A.S., vol. 78, pp. 7294-7298, 1981.
J. Med. Chem. vol. 15, No. 12, pp. 1284-1287, 1972.
J. Org. Chem., vol. 43, No. 14, pp. 2923-2925, 1978.
Surgery, vol. 92, No. 2, pp. 138-145, "Pros. for the Control of Host Defenses".
Infection, vol. 12, No. 3, pp. 230/182 to 234/86, 1984.

Affiliated with

Also associated with

Rating

Steroidal glycolipids as host resistance stimulators against vir does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Steroidal glycolipids as host resistance stimulators against vir, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroidal glycolipids as host resistance stimulators against vir will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-95108