Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1976-07-09
1977-08-23
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A61K 3156
Patent
active
040441261
ABSTRACT:
An antiinflammatory steroid exhibiting a tendency to crystal growth in suspension in aerosol propellants is contacted with a halogenated hydrocarbon to form a crystalline solvate, which, after removal of some or all of the propellant from the crystals, is reduced to a particle size permitting inhalation into the human bronchial system when dispersed as an aerosol, the micronized crystalline solvate not thereafter exhibiting crystal growth in the aerosol propellant. The solvate is a new composition of matter which has been characterized by I.R. spectra and the aerosol formulation prepared therefrom has valuable therapeutic properties, particularly in the treatment of asthma.
REFERENCES:
patent: 3312590 (1967-04-01), Elks et al.
patent: 3721687 (1973-03-01), Elks et al.
Brown et al., "British Medical Journal", of Mar. 4, 1972, pp. 585-589.
Mesley, "Chemistry and Industry", dated Sept. 11, 1965, pp. 1594-1595.
Cook Peter Barry
Hunt John Harold
Allen & Hanburys Limited
Roberts Elbert L.
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