Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibit

Details Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibit Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibit

1990-06-11

1992-08-11

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514172, 552557, 552599, 552601, 552611, A61K 3158, C07J 900, C07J 7100

Patent

active

051378825

ABSTRACT:
Invented are 3-acetic acid-steroidal compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5.alpha.-reductase including using these compounds to reduce prostate size and to treat prostatic adenocarcinoma. Also invented are intermediates used in preparing these compounds.

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