Steroidal[16.alpha.,17-c][2H]pyrroles

Details Steroidal[16.alpha.,17-c][2H]pyrroles Steroidal[16.alpha.,17-c][2H]pyrroles

1976-05-20

1977-04-19

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039745, C07J 7100

Patent

active

040187578

ABSTRACT:
Steroids having the structure ##STR1## and the 1,2-dehydro derivatives thereof, wherein R.sub.1 is hydrogen, hydroxy, ##STR2## fluorine, chlorine, or bromine; R.sub.2 is alkyl or aryl; R.sub.3 is aryl, cyano, alkylcarbonyl, arylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonyl, or arylsulfonyl; R.sub.4 is carbonyl, .beta.-hydroxymethylene, .beta.-chloromethylene or .beta.-bromomethylene; R.sub.5 is hydrogen, fluorine, chlorine or bromine; and R.sub.6 is hydrogen, fluorine, or methyl; have useful antiinflammatory activity.

REFERENCES:
patent: 3349084 (1967-10-01), Ayer et al.
patent: 3359287 (1967-12-01), Babcock et al.

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