Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing
Patent
1994-09-09
1998-11-03
Robinson, Allen J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Cyclopentanohydrophenanthrene ring system containing
540 31, 552621, 552646, C07J 100, C07J 2100
Patent
active
058311041
ABSTRACT:
The invention is directed to novel steroid intermediate products of general formula I ##STR1## The steroid intermediate products which can be isolated according to the invention are suitable for the synthesis of 13-ethyl-11-methylene-18,19-bisnor-17.alpha.-pregn-4-en-20-in-17-ol (desogestrel).
Further, processes for producing the steroid intermediate products of general formula I are described. The olefination of the 11-oxo steroids is carried out under the influence of ultrasound.
REFERENCES:
patent: 5140106 (1992-08-01), Winterfeldt et al.
patent: 5364847 (1994-11-01), Labrie et al.
Schwarz, et al, Tetrahedron, vol. 50 (36), pp. 10709-10720, Sep. 5, 1994.
Inhibiton of Peroxidations of Lipids and . . . Journal of Physicical Organic Chemistry. 1990.
Antioxidant Properties of Steroids. Mooradian, 1993.
Hydroxyestradiol-17 beta and 4-Hydroxyestradiol-17 alfa: . . . Emons, G. & Knuppen & Ball. (1981).
Comparative Properties of the Catechol Estrogene . . . Meriam, Mac-Lusky, Picard & naftolin. (1980).
The Anticonvulsiun effects of vitamin E . . . Levy, Burnham &Hwang (1991).
An Evaluation of the Anticonvulsant Effects of Vitamin E. Levy Burnham & Hwang. 1990.
Free Radical Scavenging Action of Bio-Catalyzer . . . Santiago, Osato, Hiramatsu, Edamatsu & Mori. Apr. 23, 1991.
Effects of 17Beta-Estradiol on Ciculating Adhesion Molecules. Journal of Clinical Endocrinology and Metabolism. 1994.
Chemotherapy of Arhtritis Induced in Rats . . . Newbould 1963.
A Rapid Luciferase Transfection Assy for Transcription Activation Effects and . . . Cancer Research Clinical Oncology, 1994.
Erhart Bernd
Moellmann Peter
Palme Hans-Joachim
Pfeiffer Carmen
Raethe Harald
Badio Barbara
Jenapharm GmbH
Robinson Allen J.
Striker Michael J.
LandOfFree
Steroid intermediate products and method of their production does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Steroid intermediate products and method of their production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroid intermediate products and method of their production will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-690980