Steroid hormone-antitumor derivatives

Details Steroid hormone-antitumor derivatives Steroid hormone-antitumor derivatives

1979-08-01

1981-04-07

Roberts, Elbert L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424177, C07J 4300, C07J 4100

Patent

active

042607361

ABSTRACT:
A process for producing a steroid hormone-antitumor derivative which selectively affects to tumor or cancer cells comprises reacting X group of a steroid hormone derivative having the formula ##STR1## wherein ST represents a steroid moiety having a cyclophenanthrene hydrocarbon skeleton of gonane, estrane or androstane which is bound to carboxyl group by esterifying OH group on D ring with carboxyl group; and R' represents a C.sub.1 -C.sub.4 alkylene group and X represents a halogen atom, amino group, hydroxyl group, carboxyl group or a salt thereof, with a modified or non-modified reactive group of an antitumor drug to form a binded group of --O--, --COO--, --CONH--, --NH-- or ##STR2##

REFERENCES:
patent: 4150126 (1979-04-01), Fex et al.

Affiliated with

Also associated with

Rating

Steroid hormone-antitumor derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Steroid hormone-antitumor derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroid hormone-antitumor derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-289827