Steroid derivatives and their use in radioimmunoassays

Details Steroid derivatives and their use in radioimmunoassays Steroid derivatives and their use in radioimmunoassays

1979-01-17

1980-09-09

Chan, Nickey

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603971, 424 1, 424238, 562471, C07D30906

Patent

active

042217253

ABSTRACT:
Radiolabeled steroid derivatives having the formula ##STR1## wherein St is des-hydroxy steroid moiety of (i) a hydroxy steroid intended for radioimmunoassay or (ii) a hydroxy containing derivative of a steroid intended for radioimmunoassay, said derivative having a strong affinity for the antibodies of the steroid intended for radioimmunoassay; R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4 and the asterisk (*) indicates tagging with a radioisotope, are useful as tracers in radioimmunoassays.

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Smith et al., J. Org. Chem., 26, 3856 (1961).
Pandya et al., J. Indian Chem. Soc., 34, 231 (1957).

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