Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1980-03-10
1982-08-17
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562478, C07C 5952, C07C 5968
Patent
active
043450962
ABSTRACT:
Radiolabeled steroid derivatives having the formula ##STR1## wherein St is a des-hydroxy steroid moiety of (i) a hydroxy steroid intended for radioimmunoassay or (ii) a hydroxy containing derivative of a steroid intended for radio-immunoassay, said derivative having a strong affinity for the antibodies of the steroid intended for radioimmunoassay; R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4 and the asterisk (*) indicates tagging with a radioisotope, are useful as tracers in radioimmunoassays.
REFERENCES:
patent: 2792418 (1957-05-01), Druey et al.
patent: 3013069 (1961-12-01), Wilkinson et al.
patent: 3102914 (1963-09-01), Wilkinson et al.
patent: 3810886 (1974-05-01), Rutner et al.
patent: 3855208 (1974-12-01), Rutner et al.
patent: 3925355 (1975-12-01), Piasio
patent: 3954739 (1976-05-01), Wilkinson
patent: 3981982 (1976-09-01), Oslapas et al.
patent: 4021535 (1977-05-01), Polito
Smith et al., J. American Chemical Society (1950), vol. 72, 1877.
Chemical Abstracts, vol. 79 (1973), #91742p.
Smith et al., J. Org. Chemistry, vol. 26 (1961), 3856.
Beatmann, H. J. et al., Tetrahedron Letters, vol. 25 (1969), 2101.
Pandya, Rajani K. et al., Jour. Indian Chem. Soc., vol. 34 (1957), 231.
Bernstein Jack
Varma Ravi K.
Vogt B. Richard
Weisenborn Frank L.
Barrack Donald J.
E. R. Squibb & Sons Inc.
Hendriksen L.
Levinson Lawrence S.
Trousof Natalie
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