Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1994-12-16
1997-02-04
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
540110, C07J 4300, A61K 3158
Patent
active
055998070
ABSTRACT:
This invention provides a novel steroid derivative having the structure of an ester between the carboxyl group of a quinolonecarboxylic acid and the alcoholic hydroxyl group in 21-position of asteroid compound, which has the following formula (I) (wherein R is a hydrogen atom, a methyl group or a hydroxyl group) or a pharmacologically acceptable salt thereof. ##STR1## The compound of this invention has high antibacterial activity and antiinflammatory activity.
REFERENCES:
patent: 4181669 (1980-01-01), Hansen et al.
patent: 5380839 (1995-11-01), McCall et al.
Nakagome et al., Chemical Abstracts, vol. 82, No. 21 26 May, 1975 Columbus, Ohio U.S. Abstract No. 140109K.
Isowaki Yuuichi
Ito Kazuhiko
Nakao Hidetoshi
Ogata Kazumi
Sakaue Takahiro
Bottino Anthony
Senju Pharmaceutical Co. Ltd.
Shah Mukund J.
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