Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-12-04
1981-09-15
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C07J 700, A61K 3156
Patent
active
042897645
ABSTRACT:
The invention provides a pharmaceutical composition for topical application comprising an essentially saturated solution of hydrocortisone in aqueous propylene glycol solution containing at least 15% but less than 50% by weight of propylene glycol, the proportion of hydrocortisone in the total composition being at least 0.08% but not greater than 0.4% by weight of aqueous propylene glycol and from 0.025 to 0.4% based on the total weight of the composition, the said composition being characterized by a pH in the range of 2.7 to 3.3, and the substantial absence of metallic cations. Such compositions have excellent storage stability and surprisingly high effectiveness of the hydrocortisone contained therein.
REFERENCES:
patent: 3899580 (1975-08-01), O'Neill et al.
Whitefield Martin
Yarrow Hyman
Drythanol Ltd.
Roberts Elbert L.
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