Steroid carbamates as potentiating agents

Details Steroid carbamates as potentiating agents Steroid carbamates as potentiating agents

1998-07-22

2000-04-04

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514177, 514182, 552557, 552582, 552586, 552590, A61K 3156, C07J 500, C07J 700

Patent

active

060461829

ABSTRACT:
Novel potentiating steroid carbamates having the general formula (I)

REFERENCES:
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Petrow et al. (CA106:693, abstract of Prostate (N.Y.) (1986), 9(2), 169-82.
Petrow, V. et al., "Design of Cytotoxic Steroids for Prostate Cancer," The Prostate 9:169-182 (1986).
Van Dort, M. et al., "Potential Tumor or Organ Imaging Agents--31. Radioiodinated Sterol Benzoates and Carbamates," Nucl. Med. Biol. 16-6:603-607 (1989).
Werbin, H. et al., "Steroid Alpha-Naphthylurethans," Journal of the American Chemical Society 77:4431-4432 (1955).
Wintersteiner O., et al., "Crystalline Progestin," The Journal Of Biological Chemistry 107-1:321-336 (1934).
Abstract of Yu, C.-N. et al., "Novel urethane-containing aminosteroid compounds," (1995).
Overman, L.E. et al., "Mild Procedures for Interconverting Allylic Oxygen Functionally. Cyclization-Induced [3,3] Sigmatropic Rearrangement of Allylic Carbamates," Journal Of American Chemical Society 100-15:4822-4834 (1978).

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