Steroid anaesthetics of the pregnane and 19-norpregnane series

Details Steroid anaesthetics of the pregnane and 19-norpregnane series Steroid anaesthetics of the pregnane and 19-norpregnane series

1973-05-08

1976-12-21

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955R, 2603974, 2603971, 26039745, 2603973, C07J 4300

Patent

active

039988295

ABSTRACT:
Steroid anaesthetics of the pregnane and 19-norpregnane series are described, the compounds possessing a 3.alpha.-hydroxy group, a 5.alpha.-hydrogen atom or a 4,5-double bond, a 17.alpha.-hydrogen atom, a 20-oxo group and at the 21-position a hydrocarbon group which may be substituted by an oxo, ether, hydroxy, acyloxy, esterified carboxy, thioether, thioester, heterocyclic, amino or aromatic group, or a fluorine or chlorine atom. The acetals and 20-enol ethers of compounds having a 21-formyl group are also described.

REFERENCES:
patent: 3042691 (1962-07-01), Hess et al.
patent: 3176012 (1965-03-01), Bertin
patent: 3463776 (1969-08-01), Lester et al.
patent: 3661940 (1972-05-01), Coombs et al.
patent: 3714352 (1973-01-01), Davis et al.
patent: 3862194 (1973-05-01), Woods
patent: 3883569 (1975-05-01), Phillips et al.
Fieser et al., Steroids pp. 692-696 (1959).
P'an et al., Methods in Hormone Research vol. 3 pp. 415-422 (1964).

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