Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1987-12-01
1990-03-20
Sneed, H. M. S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514319, 514462, 514428, 514510, 560162, 560116, 549499, 549331, 548528, 548253, 546195, C07C 6974, C07C12506, C07D25140, C07D43200
Patent
active
049102265
ABSTRACT:
Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase. Also invented are intermediates used in preparing these compounds.
REFERENCES:
patent: 3530170 (1970-09-01), Scribner
patent: 4317817 (1982-03-01), Blohm et al.
A useful synthesis of A-nor-.DELTA..sup.35 Steroids by Thallium Trinitnate Ring, A Cotraction of .DELTA..sup.4-5 -3-Keto steroids Enrico et al. Chemical Asst. 94:209060 (1981).
Holt Dennis A.
Levy Mark A.
Metcalf Brian W.
Lourie Alan D.
Saba J.
SmithKline Beckman Corporation
Sneed H. M. S.
Suter Stuart R.
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