Sterodial liposomes

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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264 41, 264 46, 424 71, 424 121, 4284022, 436829, 514 78, 514167, 514887, 514967, A61K 9127, A61K 9133, A61K 3722

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active

052884996

ABSTRACT:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to compositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

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