Steriod 5-alpha-reductase inhibitors

Details Steriod 5-alpha-reductase inhibitors Steriod 5-alpha-reductase inhibitors

1990-03-23

1991-05-21

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514177, 514178, 514179, 514182, 540 23, 540 95, 540100, A61K 3158, A61K 3156, C07J 7100, C07J 1700

Patent

active

050175688

ABSTRACT:
Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase. Also invented are intermediates used in preparing these compounds.

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Brooks et al., Steroids: 47:1-19 (Jan. 1986).
Ross et al., J. Org. Chem. 29: 2784-2785 (1964).

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