Sterilization of blood component separation devices

Details Sterilization of blood component separation devices Sterilization of blood component separation devices

1988-01-15

1990-07-31

Warden, Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Process disinfecting, preserving, deodorizing, or sterilizing

Using direct contact with electrical or electromagnetic...

422 99, 422102, 436177, A61L 208, G01N 100

Patent

active

049449184

ABSTRACT:
A method of sterilization is provided and a sterilized product from the method for blood separation tubes utilizing a density gradient medium comprised of ficoll and sodium diatrizoate alone or in combination with other such mediums by exposing such mediums to radiation sterilization from such sources as Cobalt 60 without any precipitation out of the components of the medium. This is achieved by the addition of a buffer to the gradient medium at a rate which will provide a specific pH level for the medium after exposure.

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"The Merck Index" 10th ed., Merck & Co., Inc., 1983 p. 433.
"Lange's Handbook of Chemistry" 13th ed., Dean, J. A., 1985, p. 7-666.
"Rapid, Quantitative Human Lymphocyte Separation and Purification in a Closed system", Molecular Immunology, 1979, vol. 16, pp. 621-624-A. A. Luderer, A. R. Zine, D. M. Hess, J. N. Henyan and G. Odstrchel.

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