Sterilization method employing a circulating gaseous sterilant

Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using disinfecting or sterilizing substance

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422 27, 422295, A01N 2700, A61L 220

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active

046379169

ABSTRACT:
A sterilization method comprising subjecting a sterilization chamber to an initial vacuum and then introducing steam to increase chamber pressure. The introduction of steam is interrupted and the chamber is brought into communication with a solution in a gaseous sterilant generator. The mixture of gaseous sterilant and chamber atmosphere are continuously circulated whereby equilibrium is established and the material to be sterilized is subject to constant temperature, pressure, sterilant concentration, and relative humidity for a period of time sufficient for sterilization. Also disclosed is an apparatus capable of performing the sterilization method comprising a sterilization chamber in combination with a gaseous sterilant generator. Formaldehyde is the preferred sterilizing agent.

REFERENCES:
patent: 1279524 (1918-09-01), Eckmann
patent: 2397292 (1946-03-01), Salle
patent: 3958935 (1976-05-01), Kowol
patent: 4004024 (1977-01-01), Eggensberger et al.
patent: 4040977 (1977-08-01), Eggensberger et al.
patent: 4239731 (1980-12-01), Gillis et al.
patent: 4410492 (1983-10-01), Kaye
patent: 4447394 (1984-05-01), Krouthen
"Studies the Use of Low Concentration of Formaldehyde with Steam at Sub-Atmospheric Pressures as a Method of Sterilising Non-Porous Heat Sensitive Items", Weymes et al., Greater Glasgow Health Board Sterilization Center, Aug. 1975.
Pickerill, J. K., "Practical System for Steam-Formaldehyde Sterilizing", Lab. Pract. (GB); vol. 24; No. 6; 6/75; pp. 401-404.

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