Sterile pharmaceutical composition and process for a...

Details Sterile pharmaceutical composition and process for a... Sterile pharmaceutical composition and process for a...

2003-03-11

2008-12-23

Henley, III, Raymond J (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

C424S001210, C424S486000

Reexamination Certificate

active

07468394

ABSTRACT:
An oil-in-water propofol emulsion that contains soybean oil and egg lecithin, which provide a source of nutrition for microorganisms. Current products include additives to act as a microbial growth retardation agent, the processes described herein detail several methods for the optimization of the innate microbial retardation capability of propofol. Using this process improves the safety of a propofol emulsion solution by controlling microbial growth without the side effects associated with growth retardation additives.

REFERENCES:
patent: 5496818 (1996-03-01), Schaupp et al.
patent: 6254853 (2001-07-01), Hendler et al.
patent: 6399087 (2002-06-01), Zhang et al.

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