Sterile parenteral composition

Details Sterile parenteral composition Sterile parenteral composition

1987-03-16

1992-01-14

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

424 10, 424649, A61K 31165, A61K 4900, A61K 3324

Patent

active

050811533

ABSTRACT:
A parenteral pharmaceutical composition comprising metoclopramide or a pharmaceutically acceptable salt thereof, and from 0 to 0.06% by weight, preferably from 0 to 0.006% by weight, of the composition of sodium metabisulphite, in combination with a pharmaceutically acceptable liquid carrier.
The use of this composition to alleviate nausea and vomiting, particularly in that associated with cancer chemotherapy is described.

REFERENCES:
patent: 4536386 (1985-08-01), Keenan
The Pharmaceutical Codex, 11th Ed., 1979, The Pharmaceutical Press, pp. 566-567.
The Merck Index, 9th Ed., pp. 801-802.
1983 Physicians' Desk Reference, 37th Ed., pp. 428 and 1634-1635.
1983 Physicians' Desk Reference, 37th Ed., Supplement B, pp. B19-B21.
1984 Physicians' Desk Reference, 38th Ed., pp. 429 and 1607-1608.
251 Jama 6 (Feb. 19, 1984).
251 Jama 24, p. 3249 (Jun. 22/29 1984).
5 Im 4, pp. 70-72 (Apr. 1984).
Consultant, p. 16 (Dec. 1984).
Cancer (Jun. 1, 1984).
1985 Physicians' Desk Reference, 39th Ed., pp. 1659-1661.
42 Am. J. Hosp. Pharm. 1 (Jan. 1985).
1986 Physicians' Desk Reference, 40th Ed., pp. 1463-1465.
1987 Physicians' Desk Reference, 41st Ed., pp. 424 and 1634-1636.
1988 Physicians' Desk Reference, 42nd Ed., pp. 424 and 1696-1698.

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