Sterile composition comprising a chelate complex for magnetic re

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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514184, 514836, 540465, 540474, 534 15, 534 16, 436173, A61B 5055

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056480636

ABSTRACT:
A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.

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Desreux, JF Inorganic Chemistry 19:1319-1324 (1980).
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Delgado, R. et al. Talanta 29:815-822 (1982).
Lauterbur, PC et al. In: Stereodynamics of Molecular Systems (ed): Sarma, Pergammon Press, Oxford pp. 453-456 (1979).
Lauterbur, PC Nature 242(5394):190-191 (1973).
Copy of U.S. Appln. Ser. No. 06/401,594, filed Jul. 26, 1982.
Desreux, J.F., "Nuclear Magnetic Resonance Spectroscopy of Lanthanide Complexes with a Tetraacetic Tetraaza Macrocycle. Unusual Conformation Properties", Inorg. Chem. 1980, vol. 19, pp. 1319-1324.

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