Sterile aerobic fermentation process

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi

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435243, 435247, 435315, C12N 114, C12N 100, C12N 132

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active

051983621

ABSTRACT:
The present invention is directed to a fermentation process and a fermenter, wherein aeration is improved by injecting substantially pure oxygen into culture medium by outside the fermenter means including a venturi located outside the main body of the fermenter. The oxygen is preferably injected at the throat of the venturi. The volume of the culture medium outside the fermenter is not greater than 5% of the total volume of the culture medium. The invention is particularly suitable for use in the fermentation of viscous cultures, such as cultures of filamentous fungi.

REFERENCES:
patent: 2822319 (1958-02-01), Monod
patent: 3183171 (1965-05-01), Schreiner
patent: 3749646 (1973-07-01), Pirt
patent: 4204042 (1980-05-01), Chelle
patent: 4782024 (1988-11-01), Scott et al.
Patent Abstracts of Japan, vol. 13, No. 107 (C-576) [3455k], 14th Mar. 1989; & JP-A-63 283 570 (DAIDO SANSO K.K.) 21-11-1988.

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