Stereoselective synthesis of β-nucleosides

Details Stereoselective synthesis of β-nucleosides Stereoselective synthesis of β-nucleosides

2006-05-02

2009-02-03

Lewis, Patrick T (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

07485716

ABSTRACT:
This invention relates to a process for stereoselectively preparing a nucleoside of the following formula:wherein R3, R4, and B are defined herein. The process includes reacting a furanose compound with a nucleobase in the presence of a halide salt. Also disclosed is another process for stereoselectively synthesizing an intermediate that can be used to make the starting compound in the first-mentioned process.

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