Stereoselective synthesis of oxazoline derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D26334

Patent

active

061439002

ABSTRACT:
The present invention relates to stereoselective synthetic method of oxazoline derivative. More particularly, it relates to a synthetic method of oxazoline derivative having the structure of formula I. ##STR1## wherein R represents phenyl, benzyl, methyl, ethyl, isopropyl, isobutyl, cyclohexyl or cyclohexylmethyl.

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Barco et al., A Chemoenzymatic Approach to Chiral Phenylisoerinates using 4-Isopropyl-2-Oxazolin-5-one as Masked Umpoled Synthon for Hydroxycarbonyl Anion, Tetrahedron Letters, 1994, 35(49):9289-9292.
Kingston et al., Synthesis of Taxol from Baccatin III via on Oxazoline Intermediate, Tetrahedron Letters, 1994, 35926):4483-4484.
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