Stereoselective resolution of phenylglycine derivatives with enz

Details Stereoselective resolution of phenylglycine derivatives with enz Stereoselective resolution of phenylglycine derivatives with enz

1981-12-21

1984-03-27

Warden, Robert J.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435813, C07B 2000

Patent

active

044395248

ABSTRACT:
The invention relates to a process for the stereo-selective resolution of DL-phenylglycine derivatives by hydrolyzing the ester or amide groups of N-acyl-L-phenylglycine esters or amides in N-acyl-DL-phenylglycine esters or amides by the action of enzymes, separating the N-acyl-D-phenylglycine esters or amides from the N-acyl-L-phenylglycines and then, if appropriate, subjecting the ester or amide groups of the D-enantiomers and the acyl groups to acid hydrolysis, characterized in that enzyme which are bonded to carriers are allowed to act on the N-acyl-DL-phenylglycine esters or amides in an inert two-phase mixture consisting of water-immiscible organic solvent and water.

REFERENCES:
patent: 3907638 (1975-09-01), Uzuki et al.
patent: 3971700 (1976-07-01), Boesten
patent: 4202943 (1980-05-01), Suhara et al.

Affiliated with

Also associated with

Rating

Stereoselective resolution of phenylglycine derivatives with enz does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stereoselective resolution of phenylglycine derivatives with enz, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stereoselective resolution of phenylglycine derivatives with enz will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1756389