Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1999-07-08
2000-10-31
Achutamurthy, Ponnathapu
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
435108, 435111, 435113, 435115, C12P 900, C12P 1300
Patent
active
061400882
ABSTRACT:
Processes for stereoselective enzymatic conversion of certain keto carboxylic acid derivatives to form the corresponding alkylamino acid compounds are described. The invention also concerns an engineered yeast host cell containing recombinant nucleic acid capable of expressing a phenylalanine dehydrogenase, as well as an engineered host cell containing recombinant nucleic acid capable of expressing a phenylalanine dehydrogenase enzyme and nucleic acid capable of expressing a formate dehydrogenase enzyme.
REFERENCES:
patent: 5508272 (1996-04-01), Robl
Donovan Mary Jo
Goldberg Steven
Hanson Ronald
Jass Paul A.
Li Wen-Sen
Achutamurthy Ponnathapu
Bristol--Myers Squibb Company
Klein Christopher A.
Rao Manjunath
Savitsky Thomas R.
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