Stereoselective process for producing dihydro-2,3-benzodiazepine

Details Stereoselective process for producing dihydro-2,3-benzodiazepine Stereoselective process for producing dihydro-2,3-benzodiazepine

1997-04-14

1999-07-06

Gupta, Yogendra N.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549441, 549443, 549444, C07D31758

Patent

active

059199547

ABSTRACT:
A process for stereoselectively forming N-substituted dihydro-2,3 benzodiazepines which are useful as AMPA receptor antagonists. The process includes an opening reduction step which sets the stereochemistry of the intermediates and the final compounds to the desired enantiomer. The reduction step may be carried out by an enzymatic reduction.

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