Stereoselective preparation of gamma-lactones

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

Reexamination Certificate

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C435S171000, C435S254100, C435S256100

Reexamination Certificate

active

07863023

ABSTRACT:
Method for stereoselectively preparing a (R) or (S) gamma-lactone consists in microbially biosynthesizing gamma-lactone, wherein the biosynthesis is carried out from a substrate selected from C5 to C20 fatty acids with the aid of a strain selected from those enabling a stereoselective hydroxylation in C4 of the substrate, in particularAspergollussp orMortierellasp. The biosynthesis of the gamma-lactone and the use thereof in perfumery and for food flavouring agents are also disclosed.

REFERENCES:
patent: 4560656 (1985-12-01), Farbood et al.
patent: 4950607 (1990-08-01), Cardillo et al.
patent: 5166366 (1992-11-01), Farbood et al.
patent: 5457036 (1995-10-01), Han et al.
patent: 41 26 997 (1993-02-01), None
patent: 0 258 993 (1988-03-01), None
patent: 0 519 481 (1992-12-01), None

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