Stereoselective adsorptive bubble process

Details Stereoselective adsorptive bubble process Stereoselective adsorptive bubble process

1995-11-29

1997-05-13

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546310, 548491, 549400, 560 39, 562430, 562433, 562553, C07D21184, C07D23910

Patent

active

056294247

ABSTRACT:
Process for enriching the concentration of an enantiomer (or a diastereomer) in a mixture of optically active isomers. The process includes preparing a solution containing the mixture of the optically active isomers and a chiral collector in which the chiral collector and the enantiomer (or diastereomer) are associated with each other. A gas is bubbled through a pool of the solution to form a foam, the surfaces of the bubbles in the foam having the chiral collector and the enantiomer (or diastereomer) preferentially adsorbed thereto so that the concentration ratio of the optically active isomers at said bubble surfaces differs from that in the bulk of the pool. The foam is moved vertically through a column above the pool such that during said movement at least a portion of the bubbles comprising the foam break thereby allowing liquid to drain toward the pool to provide an internal reflux within the column.

REFERENCES:
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Armstrong et al. "Foam Flotation Enrichment of Enantiomers" Advance ACS Abstracts, vol. 2, No. 20, (Oct. 15, 1994) pp. 4-5.

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