Stereoisomeric tricyclic bis(dioxopiperazines) and pharmaceutica

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

544 81, 544229, 544346, 544406, 544408, A61K 31535, C07D41314

Patent

active

048717363

ABSTRACT:
Stereoisomeric tricyclic bis(dioxopiperazines) of the formula ##STR1## wherein R is H or ##STR2## and the processes for the synthesis thereof are provided. The compounds are effective as antitumor or antimetastatic drugs.

REFERENCES:
Witiak et al., 28 J. Med. Chem., 1228 (1985).

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