Stereocontrolled synthesis of steroidal side chains

Details Stereocontrolled synthesis of steroidal side chains Stereocontrolled synthesis of steroidal side chains

1982-05-24

1983-12-06

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

044192878

ABSTRACT:
A method for stereospecifically synthesizing a steroidal side chain is disclosed which provides high yield, and which may be utilized with a variety of steroidal starting materials including unprotected, unsaturated steroidal alcohols. The method includes providing a first steroid having an aliphatic chain attached by a carbon-carbon double bond and contacting the first steroid with an aliphatic adduct in the presence of a Lewis acid.

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