Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure
Patent
1997-12-15
1999-09-28
Willse, David H.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Stent structure
603 12, A61F 204
Patent
active
059579757
ABSTRACT:
The present invention provides a biodegradable polymeric stent having a programmed pattern of in vivo degradation. When deployed, the stent comprises a substantially cylindrical element having two open ends and a plurality of regions circumferentially spaced around the cylindrical element and extending from one open end to the other open end of the cylindrical element. Each of the regions is configured to have a desired in vivo lifetime. One region is designed to have a shorter in vivo lifetime than the other region or regions so that when the stent is deployed within the lumen of a vessel of a patient, the cylindrical element breaks apart from one open end of the cylindrical element to the other open end of the cylindrical element within a predetermined period of time after the stent is deployed in the patient. In one preferred embodiment the stent is a formed from a biodegradable polymeric band. The band includes a head having a slot and a tongue having a catch mechanism. The cylindrical element is formed by inserting a portion of the tongue through the slot to provide a cylindrical element having a first reduced diameter configuration. Following deployment, the cylindrical element is in a second expanded diameter configuration wherein the distal catch mechanism engages the inner surface of the head and prevents radial collapse or recoil of the polymeric stent. In a second preferred embodiment, the stent is formed from a plurality of interconnected polymeric bands.
REFERENCES:
patent: 2127903 (1938-08-01), Bowen
patent: 3657744 (1972-04-01), Ersek
patent: 4279249 (1981-07-01), Vert et al.
patent: 4655711 (1987-04-01), Weissman
patent: 4693249 (1987-09-01), Schenck et al.
patent: 4733665 (1988-03-01), Palmaz
patent: 4740207 (1988-04-01), Kreamer
patent: 4770176 (1988-09-01), McGreevy et al.
patent: 4776337 (1988-10-01), Palmaz
patent: 4795458 (1989-01-01), Regan
patent: 4870966 (1989-10-01), Dellon et al.
patent: 4878906 (1989-11-01), Lindemann et al.
patent: 4879135 (1989-11-01), Greco et al.
patent: 4955377 (1990-09-01), Lennox et al.
patent: 4969896 (1990-11-01), Shors
patent: 5007926 (1991-04-01), Derbyshire
patent: 5035694 (1991-07-01), Kasprzyk et al.
patent: 5059211 (1991-10-01), Stack et al.
patent: 5078726 (1992-01-01), Kreamer
patent: 5078736 (1992-01-01), Behl
patent: 5085629 (1992-02-01), Goldberg et al.
patent: 5092841 (1992-03-01), Spears
patent: 5116318 (1992-05-01), Hillstead
patent: 5133732 (1992-07-01), Wiktor
patent: 5135536 (1992-08-01), Hillstead
patent: 5139480 (1992-08-01), Hickle et al.
patent: 5147385 (1992-09-01), Beck et al.
patent: 5163952 (1992-11-01), Froix
patent: 5178618 (1993-01-01), Kandarpa
patent: 5190540 (1993-03-01), Lee
patent: 5192307 (1993-03-01), Wall
patent: 5213580 (1993-05-01), Slepian et al.
patent: 5292321 (1994-03-01), Lee
patent: 5306286 (1994-04-01), Stack et al.
patent: 5419760 (1995-05-01), Narciso, Jr.
patent: 5421955 (1995-06-01), Lau et al.
patent: 5423885 (1995-06-01), Williams
patent: 5527337 (1996-06-01), Stack et al.
patent: 5551954 (1996-09-01), Buscemi et al.
patent: 5556413 (1996-09-01), Lam
patent: 5618299 (1997-04-01), Khosravi et al.
patent: 5637113 (1997-06-01), Tartaglia et al.
patent: 5665114 (1997-09-01), Weadock et al.
patent: 5700286 (1997-12-01), Tartaglia et al.
patent: 5728152 (1998-03-01), Mirsch, II et al.
patent: 5769883 (1998-06-01), Buscemi et al.
patent: 5788979 (1998-08-01), Alt et al.
patent: 5865723 (1999-02-01), Love
"Restinosis After Experimental Angioplasty: Intimal, Medial, and Adventitial Changes Associated with Contrictive Remolding", by LaFont, et al., Circulation Research, vol. 76, No. 6, Jun. 1995, pp. 996-1002.
"Effect of Alpha-tocopherol on Restenosis after Angioplasty in a Model of Experimental Atherosclerosis", by LaFont, et al., J. Clin. Invest., vol. 95, Mar. 1995, pp. 1018-1025.
"Evaluation of Long-Term Bioresorbability of Endoarterially Placed Poly-Lactic Acid Polymer in the New Zealand White Rabbit", LaFont, et al., 67th Scientific Sessions Abstract Form, Nov. 14-17, 1994.
"Progressive and Prolonged Inflation Reduces Hyperplasia but Increases Chronic Constriction After Angioplasty in the Atherosclerotic Rabbit", LaFont, et al., 67th Scientific Sessions Abstract Form, Nov. 14-17 1994.
Cornhill Fredrick
Garreau Henri L.
Lafont Antoine
Li Suming
Vert Michel R.
Jackson Suzette J.
The Centre National de la Recherche Scientifique
The Cleveland Clinic Foundation
The University of Montpellier I
The University Paris V, Faculte Necker
LandOfFree
Stent having a programmed pattern of in vivo degradation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stent having a programmed pattern of in vivo degradation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stent having a programmed pattern of in vivo degradation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-697292