Stent for delivery of drugs to the endothelium

Details Stent for delivery of drugs to the endothelium Stent for delivery of drugs to the endothelium

2007-05-08

2007-05-08

Kennedy, Sharon E. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C623S001420

Reexamination Certificate

active

10462907

ABSTRACT:
The present invention provides for a stent for treatment and prevention of arterial stenosis and re-stenosis. The stent for intraluminal placement within an artery and subsequent expansion for implantation in a patient comprises of a main body portion having a first end and a second end, for defining a passage for flow of blood there-through, the main body portion having an inner lumen surface and an outer lumen surface, the outer lumen surface coming into contact with the endothelium and delivering a drug composition on the outer lumen surface directly only to the endothelium for providing cell surface antithrombotic activity, wherein the anticoagulation activity in the blood plasma of a patient is not appreciably increased.

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