Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Having plural layers
Reexamination Certificate
2009-12-23
2011-11-29
Sweet, Thomas J (Department: 3738)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Having plural layers
C427S002240, C623S001150, C623S001440
Reexamination Certificate
active
08066764
ABSTRACT:
A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.
REFERENCES:
patent: 4236994 (1980-12-01), Dugdale
patent: 5222971 (1993-06-01), Willard et al.
patent: 5607463 (1997-03-01), Schwartz et al.
patent: 5649951 (1997-07-01), Davidson
patent: 5824056 (1998-10-01), Rosenberg
patent: 6096070 (2000-08-01), Ragheb et al.
patent: 6174329 (2001-01-01), Callol et al.
patent: 6387121 (2002-05-01), Alt
patent: 6716444 (2004-04-01), Castro et al.
patent: 6764505 (2004-07-01), Hossainy et al.
patent: 6805898 (2004-10-01), Wu et al.
patent: 6820676 (2004-11-01), Palmay et al.
patent: 6821624 (2004-11-01), Utsami et al.
patent: 6830747 (2004-12-01), Lang et al.
patent: 6858221 (2005-02-01), Sirhan et al.
patent: 6908624 (2005-06-01), Hossainy et al.
patent: 7208011 (2007-04-01), Shanley et al.
patent: 7481835 (2009-01-01), Pacetti et al.
patent: 7622135 (2009-11-01), Pathak et al.
patent: 2001/0039449 (2001-11-01), Johnson et al.
patent: 2003/0036794 (2003-02-01), Ragheb et al.
patent: 2003/0068355 (2003-04-01), Shanley et al.
patent: 2003/0083741 (2003-05-01), Woo et al.
patent: 2003/0088307 (2003-05-01), Shulze et al.
patent: 2003/0125800 (2003-07-01), Shulze et al.
patent: 2003/0144728 (2003-07-01), Scheuerman et al.
patent: 2003/0191354 (2003-10-01), Grabowy et al.
patent: 2003/0225450 (2003-12-01), Shulze et al.
patent: 2004/0131700 (2004-07-01), Cifra et al.
patent: 2004/0148015 (2004-07-01), Lye et al.
patent: 2004/0172124 (2004-09-01), Vallana et al.
patent: 2004/0176828 (2004-09-01), O'Brien
patent: 2005/0038498 (2005-02-01), Dubrow et al.
patent: 2005/0038505 (2005-02-01), Shulze et al.
patent: 2005/0107870 (2005-05-01), Wang et al.
patent: 2005/0187608 (2005-08-01), O'Hara
patent: 2006/0127443 (2006-06-01), Helmus
patent: 0362444 (1990-04-01), None
patent: 1454651 (2004-09-01), None
patent: 06001891 (2006-08-01), None
patent: W09936193 (1999-07-01), None
patent: WO2004105826 (2004-12-01), None
Richards, P.J., et al. “Wind Loads on Porous Structures-Its Microenvironment & Its Effects on Structural Loads.” Nov. 2009. Journal of Wind Engineering & Industrial Aerodynamics.
Frysz Christine A.
O'Brien Robert C.
Greatbatch Ltd.
Scalise Michael F.
Stewart Jason-Dennis
Sweet Thomas J
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