Stent coating for eluting medication

Details Stent coating for eluting medication Stent coating for eluting medication

2009-12-23

2011-11-29

Sweet, Thomas J (Department: 3738)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Having plural layers

C427S002240, C623S001150, C623S001440

Reexamination Certificate

active

08066764

ABSTRACT:
A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

REFERENCES:
patent: 4236994 (1980-12-01), Dugdale
patent: 5222971 (1993-06-01), Willard et al.
patent: 5607463 (1997-03-01), Schwartz et al.
patent: 5649951 (1997-07-01), Davidson
patent: 5824056 (1998-10-01), Rosenberg
patent: 6096070 (2000-08-01), Ragheb et al.
patent: 6174329 (2001-01-01), Callol et al.
patent: 6387121 (2002-05-01), Alt
patent: 6716444 (2004-04-01), Castro et al.
patent: 6764505 (2004-07-01), Hossainy et al.
patent: 6805898 (2004-10-01), Wu et al.
patent: 6820676 (2004-11-01), Palmay et al.
patent: 6821624 (2004-11-01), Utsami et al.
patent: 6830747 (2004-12-01), Lang et al.
patent: 6858221 (2005-02-01), Sirhan et al.
patent: 6908624 (2005-06-01), Hossainy et al.
patent: 7208011 (2007-04-01), Shanley et al.
patent: 7481835 (2009-01-01), Pacetti et al.
patent: 7622135 (2009-11-01), Pathak et al.
patent: 2001/0039449 (2001-11-01), Johnson et al.
patent: 2003/0036794 (2003-02-01), Ragheb et al.
patent: 2003/0068355 (2003-04-01), Shanley et al.
patent: 2003/0083741 (2003-05-01), Woo et al.
patent: 2003/0088307 (2003-05-01), Shulze et al.
patent: 2003/0125800 (2003-07-01), Shulze et al.
patent: 2003/0144728 (2003-07-01), Scheuerman et al.
patent: 2003/0191354 (2003-10-01), Grabowy et al.
patent: 2003/0225450 (2003-12-01), Shulze et al.
patent: 2004/0131700 (2004-07-01), Cifra et al.
patent: 2004/0148015 (2004-07-01), Lye et al.
patent: 2004/0172124 (2004-09-01), Vallana et al.
patent: 2004/0176828 (2004-09-01), O'Brien
patent: 2005/0038498 (2005-02-01), Dubrow et al.
patent: 2005/0038505 (2005-02-01), Shulze et al.
patent: 2005/0107870 (2005-05-01), Wang et al.
patent: 2005/0187608 (2005-08-01), O'Hara
patent: 2006/0127443 (2006-06-01), Helmus
patent: 0362444 (1990-04-01), None
patent: 1454651 (2004-09-01), None
patent: 06001891 (2006-08-01), None
patent: W09936193 (1999-07-01), None
patent: WO2004105826 (2004-12-01), None
Richards, P.J., et al. “Wind Loads on Porous Structures-Its Microenvironment & Its Effects on Structural Loads.” Nov. 2009. Journal of Wind Engineering & Industrial Aerodynamics.

Affiliated with

Also associated with

Rating

Stent coating for eluting medication does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stent coating for eluting medication, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stent coating for eluting medication will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4305474