Stent assembly for the treatment of vulnerable plaque

Details Stent assembly for the treatment of vulnerable plaque Stent assembly for the treatment of vulnerable plaque

2002-05-13

2009-08-11

Nguyen, Anhtuan T (Department: 3731)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent in combination with graft

C623S001150, C623S001420

Reexamination Certificate

active

07572286

ABSTRACT:
An intravascular stent assembly for implantation in a body lumen, such as a coronary artery, is designed to treat a lesion with vulnerable plaque by reducing the fibrous cap stresses. A polymeric sleeve having first and second ends interconnects a first metallic stent and a second metallic stent. The first end is bonded to a distal end region of the first stent and the second end to a proximal end region of the second stent. The polymeric sleeve can be loaded with a therapeutic drug or agent to further control local thrombosis and/or induce healing if the plaque fibrous cap ruptures during or after implantation. Methods of making an intravascular stent assembly for the treatment of vulnerable plaque are also provided.

REFERENCES:
patent: 5591195 (1997-01-01), Taheri et al.
patent: 5653747 (1997-08-01), Dereume
patent: 5824046 (1998-10-01), Smith et al.
patent: 5843164 (1998-12-01), Frantzen et al.
patent: 5897911 (1999-04-01), Loeffler
patent: 6143022 (2000-11-01), Shull et al.
patent: 6162246 (2000-12-01), Barone
patent: 6168619 (2001-01-01), Dinh et al.
patent: 6319278 (2001-11-01), Quinn
patent: 6432127 (2002-08-01), Kim et al.
patent: 2002/0107561 (2002-08-01), Pinheiro
Beattie, D.K., Ph.D.,Mechanical Modeling: Assessing Atherosclerotic Plaque Behavior and Stability in Humans, International Journal of Cardiovascular Medicine and Science, vol. 2, No. 2, pp. 69-81, 1999.
Cheng, George C., et al.,Distribution of Circumferential Stress in Ruptured and Stable Atherosclerotic Lesions: A Structural Analysis With Histopathological Correlation, Circulation, vol. 87, No. 4, pp. 1179-1187, Apr. 1993.
Feezor, C., et al.,Integration of Animal and Human Coronary Tissue Testing With Finite Element Techniques for Assessing Differences in Arterial Behavior, BED—Bioengineering Conference Amercian Society of Mechanical Engineers, vol. 50, pp. 135-136, Jun. 2001.
Lee, Richard T., et al.,Circumferential Stress and Matrix Metalloproteinase I in Human Coronary Atherosclerosis: Implications for Plaque Rupture, Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 16, No. 8, pp. 1070-1073, Aug. 1996.
Loree, Howard M.,Effects of Fibrous Cap Thickness on Peak Circumferential Stress in Model Atherosclerotic Vessels, Circulation Research, vol. 71, No. 4, pp. 850-858, Oct. 1992.
Richardson, P.D.,Influence of Plaque Configuration and Stress Distribution on Fissuring of Coronary Atherosclerotic Plaques, The Lancet, pp. 941-944, Oct. 21, 1989.
Veress, A.I., et al.,Finite Element Modeling of Atherosclerotic Plaque, IEEE, The Cleveland Clinic Foundatino, The Ohio State University, Columbus, OH, pp. 701-794, 1993.

Affiliated with

Also associated with

Rating

Stent assembly for the treatment of vulnerable plaque does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stent assembly for the treatment of vulnerable plaque, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stent assembly for the treatment of vulnerable plaque will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4102095