Stem cell factor analog compositions and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530350, 5303501, 530399, A61K 3818, C07K 1446

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active

058859624

ABSTRACT:
The present invention relates to stem cell factor analog polypeptide compositions, and vectors, host cells, and processes for recombinant DNA production of the present stem cell factor analogs. Pharmaceutical compositions and methods of use are also disclosed.

REFERENCES:
Langley K E; Mendiaz E A; Liu N; Narhi L O; Zeni L; Parseghian C M; Clogston C L; Leslie I; Pope J A; Lu H S; et al. Properties of variant forms of human stem cell factor recombinantly expressed in Escherichia coli . Archives of Biochemistry and Biophysi, May 1994.
Friedman A R; Ichhpurani A K; Brown D M; Hillman R M; Krabill L F; Martin R A; Zurcher-Nely H A; Guido D M. Degradation of growth hormone releasing factor analogs in neutral aqueous solution is related to deamidation of asparagine residues. Replacement, Jan. 1991.
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Langley, et al., Arch. Biochem. Biophys. 311: 55-61 (1994).
Lu, et al., Biochem. J. 305: 563-568 (1995).
Remingtons Pharmaceutical Sciences, 18th Ed. (1990), Mach Publishing Co., Easton, PA 18042, pp. 697-773.
Remingtons Pharmaceutical Sciences, 18th Ed. (1990), Mach Publishing Co., Easton, PA 18042, pp. 1435-1712.
Langley et al., Arch. Biochem. Biophys. 295: 21-28.
Smith, Kent et al., Current Protocols in Immunology (Coligan, et al., eds). Supplement 4 CPI, Unit 6, 17, pp. 6.17.1 to 6.17.11, John Wiley & Sons, New York (1992).
Zhang, et al., Biology of Reproduction 50:95-102 (1994).
Zhang, et al. Biology of Reproduction 50:95-102 (1994), see abstract, fig. 3.

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