Chemistry: molecular biology and microbiology – Apparatus – Differentiated tissue perfusion or preservation apparatus
Patent
1989-03-27
1990-10-02
Warden, Robert J.
Chemistry: molecular biology and microbiology
Apparatus
Differentiated tissue perfusion or preservation apparatus
435313, 435314, 435315, 435818, 261122, C12M 300, C10J 108
Patent
active
049607065
ABSTRACT:
A static oxygenator for oxygenating a liquid, particularly a suspension culture of animal cells in a liquid culture medium, comprised of a bottom gassing portion comprised of generally concentric vertically oriented hollow cylinders of porous gas-permeable, liquid-impermeable material, and an upper degassing section comprised of vertical extensions of the concentric cylinders such that at least one liquid overflow weir is provided at the juncture between the bottom and upper sections. Gas directed into the bottom of the annular space between the concentric cylinders rises therein and, across the porous material, oxygenates liquid in contact therewith or in proximity thereto up to the point where the liquid overflows the weir, and the gas then continues up the annular space in the vertical extensions for degassing through the porous material above the liquid level.
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Bliem Rudolf F.
Long James F.
Baxter International Inc.
Griffith Rebekah A.
Warden Robert J.
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