Start-up of continuous butyric acid fermentor

Details Start-up of continuous butyric acid fermentor Start-up of continuous butyric acid fermentor

1991-12-09

1992-07-21

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435813, 435842, C12P 752, C12R 1145

Patent

active

051322170

ABSTRACT:
A process for starting up the continuous production of butyric acid by fermentation of a medium containing a starting amount of a nutrient substrate and a microorganism that converts the nutrient into butyric acid, that avoids an excess of nutrient in the fermentation broth and comprises the steps of (1) fermenting in a fermentor in batch style an amount of the medium that is substantially less than the working volume of the fermentor until the amount of the nutrient not yet converted is no more than a small fraction of the starting amount, (2) adding medium to the fermentor without removing any of the fermentation broth, until it contains approximately its working volume, then, (3) while continuing the addition, removing the fermentation broth containing the butyric acid product at a continuous rate that maintains a constant volume of medium in the fermentor, and thereafter maintaining continuous operation of the fermentation.

REFERENCES:
patent: 4539293 (1985-09-01), Bergstrom et al.
patent: 4814273 (1989-03-01), Brumm et al.
Japanese APS Abstract J62-267 (Jan. 6, 1987) Taiji Imanishi et al.
Japanese APS PBS J61-212282 (Sep. 1986) Shirai et al.

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