Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1993-02-01
1995-06-13
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 54, 514333, 514334, 514335, 514357, 514778, 514879, 514960, 514970, 514972, A61K 31715
Patent
active
054243017
ABSTRACT:
Solid compositions of certain cholinergic compounds are stabilized in starch. Especially compositions of corn starch combined or mixed with the 0-substituted-1,2,5,6-tetrahydro-3-pyridine oxime ether, CI-979 HCl, a cognition activator, have been found stable in a heated environment of up to 60.degree. C. over 17 days such that no losses were detected by HPLC analysis. A solid peroral pharmaceutical formulation for the treatment of cognitive disorders is based on the bicomponent composition of active ingredient and stabilizer using appropriate amounts of other excipients or components known in the formulation art.
REFERENCES:
patent: 3446894 (1969-05-01), Magid
patent: 3523871 (1970-08-01), Matsuoka et al.
patent: 3533871 (1970-10-01), Zentmyer
patent: 4268265 (1981-05-01), Von Wattenwyl
patent: 4710517 (1987-12-01), Umezawa et al.
patent: 4786648 (1988-11-01), Bergmeier et al.
patent: 4812445 (1989-03-01), Eden et al.
patent: 4824938 (1989-04-01), Koyama et al.
patent: 4837241 (1989-06-01), Jensen et al.
AN 80-35636c [20] WPIDS; JP 55047615; Apr. 4, 1980.
Fawzi Mahdi B.
Huang Hua-pin
Julian Thomas N.
Radebaugh Galen W.
Wootton Scott C.
Atkins Michael J.
Griffin Ronald W.
Warner-Lambert & Company
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