Starch acetate composition with modifiable properties, method fo

Details Starch acetate composition with modifiable properties, method fo Starch acetate composition with modifiable properties, method fo

1995-01-19

1997-09-16

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424464, 424470, 424472, 514778, 536102, 536107, 536110, A61K 920, A61K 946, A61K 924, C08B 3102

Patent

active

056678037

ABSTRACT:
The present invention is related to a novel type of composition with modifiable properties and suitable for controlled release of active ingredients in industrial use. The composition contains an active ingredient and starch acetate in the form of a compact. More specifically the invention relates to active ingredients such as solid dosage forms of drugs, especially compacts and tablets. In these compacts starch acetate with distinct substitution degrees are used. The starch acetate makes the process industrially feasible with good flowability and facilitates the formation of firm tablets. Starch acetate enables the controlled release of the active ingredient. The invention also discloses method for the preparation of the composition as well as its use.

REFERENCES:
patent: 3622677 (1971-11-01), Short et al.
patent: 3795670 (1974-03-01), Mark et al.
patent: 4072535 (1978-02-01), Short et al.
Pradeepkumar P. et al, "Evaluation of Preflo Modified Starches as New Direct Compression Excipients.", Pharmaceutical Research, vol. 10, No. 11, (1993).

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