Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1992-02-14
1993-09-14
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
426541, A61K 3156
Patent
active
052448878
ABSTRACT:
Food additives containing stanols and methods for making and using the food additives. These food additives are intended to reduce cholesterol absorption from foods and beverages which contain cholesterol, e.g., meat, eggs, and dairy products. Specific stanols include sitostanol, clionastanol, 22,23 dihydrobrassicastanol, campestanol, and mixtures thereof.
REFERENCES:
patent: 3085939 (1963-04-01), Wruble et al.
patent: 3203862 (1965-08-01), Jones
patent: 3495011 (1970-02-01), Fossel
patent: 3689663 (1972-09-01), Kramer et al.
patent: 3751569 (1973-08-01), Erickson
patent: 3849554 (1974-11-01), Wintz
patent: 3865939 (1975-02-01), Jandacek
patent: 3881005 (1975-04-01), Thakkar et al.
patent: 3954976 (1976-05-01), Mattson et al.
patent: 3959492 (1976-05-01), Coulston et al.
patent: 4034083 (1977-08-01), Mattson
patent: 4117121 (1978-09-01), Gallo-Torres
patent: 4195084 (1980-03-01), Ong
patent: 4242502 (1980-12-01), Malinow et al.
patent: 4351844 (1982-09-01), Patchett et al.
patent: 4420427 (1983-12-01), Hamunen
patent: 4427668 (1984-01-01), Javitt
patent: 4602003 (1986-07-01), Malinow
patent: 4603142 (1986-07-01), Burger et al.
patent: 4680290 (1987-07-01), Cassal
patent: 4789664 (1988-12-01), Seligson
patent: 4789670 (1988-12-01), Tipton et al.
patent: 4789682 (1988-04-01), Stokker
patent: 4824672 (1989-04-01), Day et al.
patent: 4849222 (1989-06-01), Broaddus
patent: 4883788 (1989-11-01), Day et al.
patent: 4900726 (1990-02-01), Tipton et al.
patent: 4950140 (1990-08-01), Pflaumer et al.
"Lowering Blood Cholesterol to Prevent Heart Disease." Consensus Development Conference on Lowering Blood Cholesterol to Prevent-Heart Disease (NIH) J. Am. Med. Assoc. 253, 2080-2086 (1985).
National Heart Lung and Blood Institute. Report of the National Cholesterol Education Program: Expert Panel on Detection. "Evaluation and Treatment of High Blood Cholesterol Levels in Adults." Arch. Int. Med. 148, 36-39 (1988).
"Successful Prevention of Experimental Hypercholesterolemia and Cholesterol Atheroschlerosis in the Rabbit." Pollak, O. J. Circulation 7, 696-701 (1953).
"The Effect of Beta Sitosterol in the Serum Lipids of Young Men with Arteriosclerotic Heart Disease." Farquhar, J. W. Smith, R. E., and Dempsey, M. E. Circulation 14, 77-82 (1956).
"Effects of Plant Sterols on Cholesterol Metabolism in Man." Kudchodkar, B. J., Horlick, L., and Sodhi, H. S. Atherosclerosis 23, 239-248 (1976).
"Plant Sterols as Cholesterol-Lowering Agents: Clinical Trials in Patients with Hypercholesterolemia and Studies of Sterol Balance", Lees, A. M., Mok, H. Y. I., Lees, R. S., McCluskey, M. A. and Grundy S. M. Atherosclerosis 28, 325-388 (1977).
"Response of Serum Lipids and Lipoproteins of Man to beta-sitosterol and Safflower Oil. A Long Term Study." J. W. and Sokolow, M. Circulation 17, 890-899 (1958).
"Dietary Plant Sterols: Current status in human and animal sterol metabolism." Subbisah, M. T. Ravi, Am.
"Effect of Low-Dose Sitostanol on Serum Cholesterol in Patients with Hypercholesterolemia." Heinemann, T., Leiss, O. and von Vergmann, K. Atheroschlerosis, 61, 219-233 (1986).
"Comparison of Sitosterol and Sitostanol on Inhibition of Intestinal Cholesterol Absorption." Heinemann, T., Pietruck, B. Kullak-Ubilick, G. and von Bergmann, K. 4th Cologne Atherosclerosis Conference 1988. Birkhauser Verlag, Basel p. 117.
"Comparison of Absorption and Metabolism of .beta.-Sitosterol and.beta.-Sitostanol in Rats." Ikeda, I and Sugano M. Atherosclerosis 30, 227-237 (1978).
"Some Aspects of Mechanisms of Inhibition of Cholesterol Absorption of .beta.-Sitostersol". Ikeda, I. and Sugano, M. Biochem. Biophys. Acta 732, 651-658 (1983).
"Optimizing the Effect of Plant Sterols on Cholesterol Absorption in Man." Mattson, F. H., Grundy, S. M., and Crouse, J. R. Am. J. Clin. Nutr. 35, 697-700 (1982).
"Effect of Plant Sterols on Serum Lipids and Atherosclerosis." Pollack, O. J. Pharmac. Ther. 31, 177-208 (1985).
The Lipids. vol. 1, Deuel, H. J. Jr. Interscience Publishers, 1951, New York, pp. 348-361.
Cintins Marianne M.
Cook Rebecca
LandOfFree
Stanols to reduce cholesterol absorption from foods and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stanols to reduce cholesterol absorption from foods and methods , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stanols to reduce cholesterol absorption from foods and methods will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2026634