Radiant energy – Invisible radiation responsive nonelectric signalling – Luminescent device
Reexamination Certificate
2008-07-08
2008-07-08
Porta, David P. (Department: 2884)
Radiant energy
Invisible radiation responsive nonelectric signalling
Luminescent device
Reexamination Certificate
active
11335140
ABSTRACT:
A free-space standoff optical detection platform for any detection scheme based on spontaneous emissions, such as for example, fluorescence detection. More particularly, the present invention relates to a detection system having SPCE beads. In one embodiment, the SPCE beads are dielectric spheres coated with a thin metal layer, which supports surface plasmon resonance (SPR) at the operation wavelength. For fluorescence detection, fluorescence reporters can be coated outside of SPCE beads. Upon the presence of the analyte, the fluorescence reporter changes its emitting signal. The SPCE beads amplify the field strength of the excitation via the lens effect and SPR enhancement. The spontaneous emitting signal is collected via the coupling between the SPR and emission, which results high collection efficiency and signal-to-noise ratio. This surface plasmon-coupled emission (SPCE) signal propagates in the beads in a curved path dictated by the SPR condition. Finally, the SPCE signal is collimated by the beads and sent back to the standoff interrogator. Further, the SPCE beads may be spread over the target region and interrogated over a distance.
REFERENCES:
patent: 2005/0053974 (2005-03-01), Lakowicz et al.
Lakowicz, Radiative decay engineering 3. Surface plasmon-coupled directional emission,2003,Analytical Biochemistry,324,153-169.
Gryczynski et al., Radiative decay engineering 4. Experimental studies of surface plasmon-coupled directional emission,2003,Analytical Biochemistry,324,170-182.
J. R. Lakowicz, “Radiative decay engineering 3. Surface plasmon-coupled directional emission,”Analytical Biochemistry, 324, pp. 153-169, (2004).
I. Gryczynski, J. Malicka, Z. Gryczynski, and J. R. Lakowicz, “Radiative decay engineering 4. Experimental studies of surface plasmon-coupled directional emission,”Analytical Biochemistry, 324, pp. 170-182, (2004).
Jorg Enderlein, Thomas Ruckstuhl, and Stefan Seeger, “Highly efficient optical detection of surface-generated fluorescence,”Applied Optics, vol. 38, issue 4, pp. 724-732, (1999).
J. Enderlein, “Single-molecule fluorescence near a metal layer,”Chemical Physics, 247, pp. 1-9, (1999).
W. H. Weber and C. F. Eagen, “Energy transfer from an excited dye molecule to the surface plasmons of an adjacent metal,”Optical Letters, vol. 4, issue 8, pp. 236-238, (1979).
G. W. Ford and W. H. Weber, “Electromagnetic interactions of molecules with metal surfaces,”Physics Reports, vol. 113, No. 4, pp. 195-287, Nov. 1984.
R. W. Gruhike and D. G. Hall, “Transmission of molecular fluorescence through a thin metal film by surface plasmons,”Applied Physics Letters, vol. 53, No. 12, pp. 1041-1042, Sep. 1988.
R. E. Benner, R. Dornhaus, and R. K. Chang, “Angular emission profiles of dye molecules excited by surface plasmon waves at a metal surface,”Optics Communications, vol. 30, Issue 2, pp. 145-149, Aug. 1979.
S. C. Kitson, W. L. Barnes, and J. R. Sambles, “Photoluminescence from dye molecules on silver gratings,”Optics Communications, vol. 122, issue 4-6, pp. 147-154, Jan. 1, 1996.
R. R. Chance, A. Prock, and R. Silbey, “Molecular Fluorescence and Energy Transfer Near Interfaces” in Advances in Chemical Physics, ed by I. Prigogine and S.A. Rice, eds, vol. 37, 1, Wiley, 1978.
Dunlap Codding & Rogers P.C.
Malevic Djura
Nomadics, Inc.
Porta David P.
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