Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Protein or peptide standard or control
Patent
1981-07-16
1984-08-14
Gron, Teddy S.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Protein or peptide standard or control
436 13, 436 16, 436 17, 436 66, 436 67, 424101, 435 2, 435188, C09K 300, G01N 3372, G01N 3396
Patent
active
044657749
ABSTRACT:
A control material for use in the determination of glycosylated and total hemoglobin, and a method of preparing the same, are disclosed. The control is prepared by the steps of hemolyzing red blood cells, preferably in the presence of a detergent, followed by removal of stroma and lipids from the hemoglobin with an organic solvent such as toluene in the presence of a polyhydroxy compound such as sucrose. A hemoglobin-rich fraction is separated from the resulting mixture and dialyzed against a solution of a polyhydroxy compound. The dialysate may be lyophilized to provide a stable, dry product suitable for reconstitution.
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Chen Jung-Shou
Huang John J.
Mezei Louis M.
Garber Stanley N.
Gron Teddy S.
O'Meara William R.
Sherwood Medical Company
Upchurch Gregory E.
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