Stably-transformed cells expressing human thiopurine methyltrans

Details Stably-transformed cells expressing human thiopurine methyltrans Stably-transformed cells expressing human thiopurine methyltrans

1994-10-03

1995-11-28

Low, Christopher S. F.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351723, 4353201, 435193, 536 231, 536 235, 536 232, C12N 510, C12N 910, C07H 1512

Patent

active

054707374

ABSTRACT:
A recombinant DNA sequence is provided which encodes human thiopurine methyl transferase (TPMT), as well as a mammalian cell line having said recombinant DNA sequence incorporated into the genome thereof, so that the cells express high levels of human TPMT activity.

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