Stable water-in-oil emulsions

Details Stable water-in-oil emulsions Stable water-in-oil emulsions

1997-11-26

2000-01-11

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

424439, 436601, 436602, A61K 9107, A61K 3843

Patent

active

060132558

ABSTRACT:
The present invention describes stable water-in-oil emulsions comprising the following components: water, oil, a labile compound of interest, a stabilizing agent and an emulsifier. The labile compound present in the water phase is stabilized by addition of a stabilizing agent which preferably is a polyol. Specific emulsifiers are described which give rise to stable emulsions in the presence of high amounts of a polyol.

REFERENCES:
patent: 3958033 (1976-05-01), Sims et al.
patent: 3966632 (1976-06-01), Colliopoulos et al.
patent: 4869919 (1989-09-01), Lowery
patent: 4985173 (1991-01-01), Takahashi et al.
patent: 5085856 (1992-02-01), Dunphy et al.
patent: 5306517 (1994-04-01), Norton et al.
Lillehaug, A., "Oral immunization of rainbow trout, Salmo gairdneri Richardson, against vibriosis with vaccines protected against digestive degradation," Journal of Fish Diseases 1989, 12, 579-584.
Abstract of Japan 50-86368.

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