Stable topical formulations with good active ingredient release

Details Stable topical formulations with good active ingredient release Stable topical formulations with good active ingredient release

1993-10-04

1995-12-19

Lilling, Herbert J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 28, 514 30, 514291, 536 71, 536 72, 536 74, C07H 1708, A61K 3170

Patent

active

054768438

ABSTRACT:
A stable topical formulation with good active ingredient release characteristics, comprising at least one macrolide antibiotic which is lipophilized with at least one former of oppositely charged ions which is selected from the group consisting of alkyl sulfates, alkylsulfonates, and alkyl salicylates, RX, where R represents a linear and/or branched alkyl group with 6-32 C atoms, and X represents a sulfate, sulfonate, or salicylate group.

REFERENCES:
patent: 3891755 (1975-06-01), Mehta
patent: 3922379 (1975-11-01), Farhadieh
patent: 3934013 (1976-01-01), Poulsen
patent: 4091090 (1978-05-01), Sipos
patent: 4474748 (1984-10-01), Sipos

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