Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1978-10-13
1980-01-15
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 49, 424 54, 424 57, A61K 716, A61K 718, A61K 722
Patent
active
041839153
ABSTRACT:
An aqueous solution useful for remineralizing subsurface carious lesions of dental enamel which solution contains sources of calcium ions and phosphate ions as well as fluoride ions and further includes as an agent to stabilize the solution against precipitation, an antinucleating agent such as ethylenediamine tetramethylenephosphonic acid or water soluble salt thereof, the pH of the solution being about 5-9, preferably close to physiological conditions, such as about 6.8-7.5.
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Meyer and Nancollas Calc. Tiss. Res. 13:295-303 (1973), The Influence of Multi-Dentate Organo-Phosphonates on the Crystal Growth of Hydroxy Apatite.
Briner et al., Calc. Tiss. Res. 7:249-256 (1971), Factors Affecting the Rate of Post-Eruptive Maturation of Dental Enamel.
Monsanto Co. Brochure "Dequest" Organophosphorus Compounds, Feb. 1971.
Gaffar Abdul
Gaffar Maria C. S.
Colgate-Palmolive Company
Grill Murray M.
Rose Shep K.
Stone Robert L.
Sylvester Herbert S.
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