Stable sodium acetylsalicylate and method for its manufacture

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07C 6914

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039857921

ABSTRACT:
A novel crystalline form of sodium acetylsalicylate (sodium aspirin) is obtained by first precipitating sodium aspirin dihydrate in crystalline form and thereafter dehydrating it to form anhydrous sodium aspirin. The process is carried out under controlled conditions and the product exhibits high storage stability and other desirable physical properties.

REFERENCES:
patent: 1217862 (1917-02-01), Gerngross et al.
patent: 3064038 (1962-11-01), Adams
patent: 3109019 (1963-10-01), Schlosser
Malkin, Chem. Abstracts, vol. 52 (1958), p. 12499.
Beilstein, vol. 10, 1st Supp. p. 29.

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