Stable shaped particles of crystalline organic compounds

Details Stable shaped particles of crystalline organic compounds Stable shaped particles of crystalline organic compounds

2003-02-26

2008-09-23

Woodward, M P (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S408000, C424S439000, C424S451000, C424S457000, C424S458000, C424S465000, C424S469000

Reexamination Certificate

active

07427413

ABSTRACT:
The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

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